Product Datasheet
TALDO1 Antibody
Catalog Number: 42784
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P37837
Gene ID: 6888
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human TALDO1
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- TAL; TALH; TAL-H; TALDOR
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TALDO1 protein.
- Background:
- Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
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