Product Datasheet
TRIM21 Antibody
Catalog Number: 42767
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P19474
Gene ID: 6737
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human TRIM21
- appl_detail:
Immunohistochemistry: 1:25-1:100
- other_names:
- SSA; RO52; SSA1; RNF81; Ro/SSA
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TRIM21 protein.
- Background:
- This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.?
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