Product Datasheet
SLC25A13 Antibody
Catalog Number: 42757
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UJS0
Gene ID: 10165
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human SLC25A13
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:200
- other_names:
- CTLN2; CITRIN; ARALAR2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SLC25A13 protein.
- Background:
- This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.?
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