Product Datasheet
SRPX Antibody
Catalog Number: 42756
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P78539
Gene ID: 8406
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human SRPX
- appl_detail:
- Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:25-1:100
- other_names:
- DRS; ETX1; SRPX1; HEL-S-83p
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SRPX protein.
- Background:
- SRPX gene also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor.
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