Product Datasheet  
SRPX Antibody  
Catalog Number: 42756  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P78539
    Gene ID: 8406
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein of human SRPX
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:1000-1:5000
    Immunohistochemistry: 1:25-1:100
  • other_names:  
  • DRS; ETX1; SRPX1; HEL-S-83p
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total SRPX protein.
  • Applications:  
  • WB IHC
  • Background:  
  • SRPX gene also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor.



 
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