Product Datasheet
LTA4H Antibody
Catalog Number: 42720
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P09960
Gene ID: 4048
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human LTA4H
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:10-1:50
- other_names:
- Leukotriene A-4 hydrolase; leukotriene A4 hydrolase; LKHA4; LTA-4 hydrolase; LTA4; LTA4H
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total LTA4H protein.
- Background:
- LTA4H (Leukotriene A4-hydrolase ) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity. As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline. The human LTA4H gene encodes a 610 amino acid protein.
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