Product Datasheet
HDAC1 Antibody
Catalog Number: 42706
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13547
Gene ID: 3065
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human HDAC1
- appl_detail:
Immunohistochemistry: 1:40-1:150
- other_names:
- HD1; RPD3; GON-10; RPD3L1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HDAC1 protein.
- Background:
- Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
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