Product Datasheet  
GRB2 Antibody  
Catalog Number: 42705  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P62993
    Gene ID: 2885
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Full length fusion protein of human GRB2
  • reactivity：  
  • Hu Rt
  • appl_detail：  

  • Immunohistochemistry: 1:25-1:100
  • other_names：  
  • ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total GRB2 protein.
  • Applications：  
  • IHC
  • Background：  
  • The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.



 
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