Product Datasheet
IL21 Polyclonal Antibody
Catalog Number: 42683
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9HBE4
- Form of Antibody:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Immunogen:
- Recombinant human Interleukin-21 protein(25-162aa)
- appl_detail:
Immunohistochemistry: 1:20 - 1:200
- other_names:
- IL-21, Za11, IL21
- Purification:
- Antigen Affinity Purified
- Specificity:
- The antibody detects endogenous level of total IL21 polyclonal antibody.
- Background:
- Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
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