Product Datasheet
CDC16 Polyclonal Antibody
Catalog Number: 42650
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q13042
- Form of Antibody:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Immunogen:
- Recombinant human Cell division cycle protein 16 homolog protein (371-620aa)
- appl_detail:
- Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
- other_names:
- Anaphase-promoting complex subunit 6, APC6, CDC16 homolog, CDC16Hs, Cyclosome subunit 6, CDC16, ANAPC6
- Purification:
- Antigen Affinity Purified
- Specificity:
- The antibody detects endogenous level of total CDC16 polyclonal antibody.
- Background:
- Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
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