Product Datasheet  
Adiponectin Polyclonal Antibody  
Catalog Number: 42649  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q15848
  • Form of Antibody：  
  • Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant human Adiponectin protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500 - 1:1000
  • other_names：  
  • 30 kDa adipocyte complement-related protein Adipocyte complement-related 30 kDa protein Adipocyte, C1q and collagen domain-containing protein Adipose most abundant gene transcript 1 protein Gelatin-binding protein ADIPOQ ACDC, ACRP30, APM1, GBP28
  • Purification：  
  • Caprylic Acid Ammonium Sulfate Precipitation purified
  • Specificity：  
  • The antibody detects endogenous level of total Adiponectin polyclonal antibody.
  • Applications：  
  • WB
  • Background：  
  • Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.



 
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