Product Datasheet  
ptxA Polyclonal Antibody  
Catalog Number: 42634  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P04977
  • Form of Antibody：  
  • Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant Bordetella pertussis Pertussis toxin subunit 1 protein
  • reactivity：  
  • Bordetella pertussis
  • appl_detail：  
  • Western blotting: 1:500 - 1:1000
  • other_names：  
  • Islet-activating protein S1 NAD-dependent ADP-ribosyltransferase ptxA BP3783
  • Purification：  
  • Caprylic Acid Ammonium Sulfate Precipitation purified
  • Specificity：  
  • The antibody detects endogenous level of total ptxA polyclonal antibody.
  • Applications：  
  • WB
  • Background：  
  • S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD+ into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.



 
© Signalway Biotechnology All Rights Reserved.