Product Datasheet
Transcription factor SOX-2 Polyclonal Antibody
Catalog Number: 42604
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P48431
- Form of Antibody:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Immunogen:
- Recombinant human Transcription factor SOX-2 protein
- appl_detail:
- Western blotting: 1:500 - 1:1000
- Purification:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Specificity:
- The antibody detects endogenous level of total Transcription factor SOX-2 polyclonal antibody.
- Background:
- Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 By similarity. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal By similarity. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation
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