Product Datasheet
Complement factor B Polyclonal Antibody
Catalog Number: 42533
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P00751
- Form of Antibody:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Immunogen:
- Recombinant human Complement factor B protein
- appl_detail:
- Western blotting: 1:500 - 1:1000
- other_names:
- C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, CFB, BF, BFD
- Purification:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Specificity:
- The antibody detects endogenous level of total Complement factor B polyclonal antibody.
- Background:
- Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
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