Product Datasheet  
Complement factor B Polyclonal Antibody  
Catalog Number: 42533  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P00751
  • Form of Antibody:  
  • Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant human Complement factor B protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500 - 1:1000
  • other_names:  
  • C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, CFB, BF, BFD
  • Purification:  
  • Caprylic Acid Ammonium Sulfate Precipitation purified
  • Specificity:  
  • The antibody detects endogenous level of total Complement factor B polyclonal antibody.
  • Applications:  
  • WB
  • Background:  
  • Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.



 
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