Product Datasheet
Ras-related GTP-binding protein A Polyclonal Antibody
Catalog Number: 42394
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q7L523
- Form of Antibody:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Immunogen:
- Recombinant human Ras-related GTP-binding protein A protein
- appl_detail:
- Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
- other_names:
- Adenovirus E3 14.7 kDa-interacting protein 1, RRAGA, FIP-1
- Purification:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Specificity:
- The antibody detects endogenous level of total Ras-related GTP-binding protein A polyclonal antibody.
- Background:
- Involved in the RCC1/Ran-GTPase pathway. RRAGA may play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. biquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.
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