Product Datasheet  
SRGN Polyclonal Antibody  
Catalog Number: 42330  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P10124
  • Form of Antibody：  
  • PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant human Serglycin protein(28-158aa)
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500 - 1:2000
    Immunohistochemistry: 1:20 - 1:200
  • other_names：  
  • Hematopoietic proteoglycan core protein, Platelet proteoglycan core protein, Secretory granule proteoglycan core protein, SRGN, PRG, PRG1
  • Purification：  
  • Antigen Affinity Purified
  • Specificity：  
  • The antibody detects endogenous level of total SRGN polyclonal antibody.
  • Applications：  
  • WB IHC
  • Background：  
  • Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.



 
© Signalway Biotechnology All Rights Reserved.