Product Datasheet  
PAX4 Polyclonal Antibody  
Catalog Number: 42287  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O43316
  • Form of Antibody：  
  • PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant human Paired box protein Pax-4 protein(50-200aa)
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500 - 1:2000
    Immunohistochemistry: 1:20 - 1:200
  • other_names：  
  • Paired box protein Pax-4, PAX4
  • Purification：  
  • Antigen Affinity Purified
  • Specificity：  
  • The antibody detects endogenous level of total PAX4 polyclonal antibody.
  • Applications：  
  • WB IHC
  • Background：  
  • Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.



 
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