Product Datasheet  
NR2C1 Polyclonal Antibody  
Catalog Number: 42274  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P13056
  • Form of Antibody：  
  • PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant human Nuclear receptor subfamily 2 group C member 1 protein(1-240aa)
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500 - 1:2000
    Immunohistochemistry: 1:20 - 1:200
  • other_names：  
  • Orphan nuclear receptor TR2, Testicular receptor 2, NR2C1, TR2
  • Purification：  
  • Antigen Affinity Purified
  • Specificity：  
  • The antibody detects endogenous level of total NR2C1 polyclonal antibody.
  • Applications：  
  • WB IHC
  • Background：  
  • Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.



 
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