Product Datasheet
ATP-sensitive inward rectifier potassium channel 1 Polyclonal Antibody
Catalog Number: 42228
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P48048
- Form of Antibody:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Immunogen:
- Recombinant huaman ATP-sensitive inward rectifier potassium channel 1 protein
- appl_detail:
- Western blotting: 1:500 - 1:1000
- other_names:
- ATP-regulated potassium channel ROM-K Inward rectifier K(+) channel Kir1.1 Potassium channel, inwardly rectifying subfamily J member 1 KCNJ1 ROMK1
- Purification:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Specificity:
- The antibody detects endogenous level of total ATP-sensitive inward rectifier potassium channel 1 polyclonal antibody.
- Background:
- In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium.
© Signalway Biotechnology All Rights Reserved.