Product Datasheet
ICOSLG Polyclonal Antibody
Catalog Number: 42215
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O75144
- Form of Antibody:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Immunogen:
- Recombinant human ICOS ligand protein (19-256aa)
- appl_detail:
Immunohistochemistry: 1:20 - 1:200
- other_names:
- B7 homolog 2, B7-H2, B7-like protein Gl50, B7-related protein 1, B7RP-1, CD275, ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
- Purification:
- Antigen Affinity Purified
- Specificity:
- The antibody detects endogenous level of total ICOSLG polyclonal antibody.
- Background:
- Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
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