Product Datasheet  
Spliceosome RNA helicase DDX39B Polyclonal Antibody  
Catalog Number: 42086  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q13838
  • Form of Antibody:  
  • Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant human Spliceosome RNA helicase DDX39B protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500 - 1:1000
    Immunohistochemistry: 1:20 - 1:200
  • other_names:  
  • 56 kDa U2AF65-associated protein ATP-dependent RNA helicase p47 DEAD box protein UAP56 HLA-B-associated transcript 1 protein
  • Purification:  
  • Caprylic Acid Ammonium Sulfate Precipitation purified
  • Specificity:  
  • The antibody detects endogenous level of total Spliceosome RNA helicase DDX39B polyclonal antibody.
  • Applications:  
  • WB
  • Background:  
  • Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.



 
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