Product Datasheet
NAA10 Polyclonal Antibody
Catalog Number: 42070
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P41227
- Form of Antibody:
- PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Immunogen:
- Recombinant human N-alpha-acetyltransferase 10 protein(161-235aa)
- appl_detail:
- Western blotting: 1:500 - 1:5000
Immunohistochemistry: 1:20 - 1:200
- other_names:
- N-alpha-acetyltransferase 10, N-terminal acetyltransferase complex ARD1 subunit homolog A, NatA catalytic subunit Naa10, NAA10, ARD1, ARD1A, TE2
- Purification:
- Antigen Affinity Purified
- Specificity:
- The antibody detects endogenous level of total NAA10 polyclonal antibody.
- Background:
- Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development.
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