Product Datasheet  
Integrin-linked protein kinase Polyclonal Antibody  
Catalog Number: 42192  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q13418
  • Form of Antibody:  
  • Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant human Integrin-linked protein kinase protein
  • reactivity:  
  • Hu
  • appl_detail:  

  • Immunohistochemistry: 1:20 - 1:200
  • other_names:  
  • 59 kDa serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK
  • Purification:  
  • Caprylic Acid Ammonium Sulfate Precipitation purified
  • Specificity:  
  • The antibody detects endogenous level of total Integrin-linked protein kinase polyclonal antibody.
  • Applications:  
  • IHC
  • Background:  
  • Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.



 
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