Product Datasheet
SMARCA2 Antibody
Catalog Number: 37955
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P51531
NCBI Gene ID: 6595
Gene Accssion: NP_003061/P51531
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- BRM; SNF2; SWI2; hBRM; NCBRS; Sth1p; BAF190; SNF2L2; SNF2LA; hSNF2a
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SMARCA2 protein.
- Background:
- The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin.?
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