Product Datasheet
SMAGP Antibody
Catalog Number: 37954
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q0VAQ4
NCBI Gene ID: 57228
Gene Accssion: NP_001026798/Q0VAQ4
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human small cell adhesion glycoprotein
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SMAGP protein.
- Background:
- SMAGP (small transmembrane and glycosylated protein) is a 97 amino acid single-pass type III membrane protein that localizes to the membrane of cytoplasmic vesicles. Existing as a murine-specific protein, SMAGP is thought to play a role in epithelial cell-cell contacts and, via its ability to control cell adhesion, may be involved in tumor formation, as well as overall tumor invasiveness and metastasis. SMAGP is subject to post-translational O-glycosylation which is thought to be modified with sialic acid residues. The gene encoding SMAGP maps to murine chromosome 15.
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