Product Datasheet
ROBO2 Antibody
Catalog Number: 37879
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9HCK4
NCBI Gene ID: 6092
Gene Accssion: NP_001122401/Q9HCK4
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human roundabout, axon guidance receptor, homolog 2 (Drosophila)
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ROBO2 protein.
- Background:
- The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants.
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