Product Datasheet
RNF148 Antibody
Catalog Number: 37874
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8N7C7
NCBI Gene ID: 378925
Gene Accssion: NP_932351/Q8N7C7
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human ring finger protein 148
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- MGC35222; RING finger protein 148; RN148; RNF148
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total RNF148 protein.
- Background:
- RNF148 (RING finger protein 148) is a 305 amino acid single-pass membrane protein that contains one PA (protease associated) domain and a single RING-type zinc finger. RNF148 is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.
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