Product Datasheet
CENPV Antibody
Catalog Number: 37846
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q7Z7K6
NCBI Gene ID: 201161
Gene Accssion: NP_859067/Q7Z7K6
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human centromere protein V
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200
- other_names:
- p30; PRR6; CENP-V; 3110013H01Rik
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CENPV protein.
- Background:
- CENPV?orthologs were detected in a range of species, including plants, but the proline-rich region was detected only in primates, rodents, birds, and amphibians, and long proline stretches were found only in primates. Northern blot analysis showed ubiquitous?Cenpv?expression in mouse tissues, with highest expression in testis, followed by small intestine, brain, and kidney. Immunofluorescence microscopy of mouse fibroblasts revealed colocalization of?Cenpv?with stabilized cytoplasmic microtubules. Western blot analysis of Ramos B cells detectedCENPV?at an apparent molecular mass of 40 kD.
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