Product Datasheet
PARP4 Antibody
Catalog Number: 37796
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UKK3
NCBI Gene ID: 143
Gene Accssion: NP_006428
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human poly (ADP-ribose) polymerase family, member 4
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- PH5P; p193; ARTD4; PARPL; VPARP; VWA5C; PARP-4; VAULT3; ADPRTL1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PARP4 protein.
- Background:
- This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.?
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