Product Datasheet
NEFM Antibody
Catalog Number: 37760
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P07197
NCBI Gene ID: 4741
Gene Accssion: NP_005373
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human neurofilament, medium polypeptide
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- NFM; NEF3; NF-M
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NEFM protein.
- Background:
- Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.?
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