Product Datasheet
MGLL Antibody
Catalog Number: 37738
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q99685
NCBI Gene ID: 11343
Gene Accssion: NP_001003794
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human monoglyceride lipase
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- MGL; HUK5; MAGL; HU-K5
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MGLL protein.
- Background:
- This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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