Product Datasheet
TNPO1 Antibody
Catalog Number: 37732
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q92973
NCBI Gene ID: 3842
Gene Accssion: NP_002261
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human transportin 1
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- MIP; TRN; IPO2; MIP1; KPNB2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TNPO1 protein.
- Background:
- This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.
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