Product Datasheet
MIG7 Antibody
Catalog Number: 37730
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q1AHR6
NCBI Gene ID: 723788
Gene Accssion: ABF71424
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human mig-7
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MIG7 protein.
- Background:
- MIG7 is a cysteine-rich protein found in cell membranes and cytoplasm of carcinoma cells. Tumor tissue and blood from over 200 cancer patients have been shown to express MIG7, regardless of tissue origin. In contrast, it has not been detectable in tissues or blood from normal subjects. Expression of MIG7 seems to be restricted to carcinoma cells and putatively to the early placenta (Cytotrophoblast) and it's expression is important for the invasive capabilities of tumor cells.
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