Product Datasheet
MFSD2A Antibody
Catalog Number: 37724
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8NA29
NCBI Gene ID: 84879
Gene Accssion: NP_001129965
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human major facilitator superfamily domain containing 2A
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MFSD2A protein.
- Background:
- MFSD2 (major facilitator superfamily domain containing 2), also known as MFSD2A, is a 543 amino acid multi-pass membrane protein of the endoplasmic reticulum that is involved in beta-adrenergic signaling during thermogenesis. Existing as three alternatively spliced isoforms, MFSD2 plays a role in G1 regulation and is encoded by a gene that maps to human chromosome 1p34.2. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson¡¯s disease, Gaucher disease, schizophrenia and Usher syndrome.
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