Product Datasheet
MAPKAPK2 Antibody
Catalog Number: 37715
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P49137
NCBI Gene ID: 9261
Gene Accssion: NP_116584/P49137
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human mitogen-activated protein kinase-activated protein kinase 2
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- MK2; MK-2; MAPKAP-K2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MAPKAPK2 protein.
- Background:
- This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
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