Product Datasheet
MAGEE1 Antibody
Catalog Number: 37710
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9HCI5
NCBI Gene ID: 57692
Gene Accssion: NP_065983
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human melanoma antigen family E, 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- HCA1; DAMAGE
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MAGEE1 protein.
- Background:
- This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to mental retardation.
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