Product Datasheet
KCNK9 Antibody
Catalog Number: 37678
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9NPC2
NCBI Gene ID: 51305
Gene Accssion: NP_001269463
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human potassium channel, subfamily K, member 9
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:300
- other_names:
- KT3.2; TASK3; K2p9.1; TASK-3
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KCNK9 protein.
- Background:
- This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants.
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