Product Datasheet
KDM4A Antibody
Catalog Number: 37671
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O75164
NCBI Gene ID: 9682
Gene Accssion: NP_055478
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human lysine (K)-specific demethylase 4A
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- JMJD2; JHDM3A; JMJD2A; TDRD14A
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KDM4A protein.
- Background:
- This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.?
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