Product Datasheet  
ITPR1 Antibody  
Catalog Number: 37665  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q14643
    NCBI Gene ID: 3708
    Gene Accssion: NP_001093422
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human inositol 1,4,5-trisphosphate receptor, type 1
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Immunohistochemistry: 1:50-1:200
  • other_names：  
  • ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total ITPR1 protein.
  • Applications：  
  • IHC
  • Background：  
  • This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.



 
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