Product Datasheet
INPPL1 Antibody
Catalog Number: 37660
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O15357
NCBI Gene ID: 3636
Gene Accssion: NP_001558
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human inositol polyphosphate phosphatase-like 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- OPSMD; SHIP2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total INPPL1 protein.
- Background:
- The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.
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