Product Datasheet  
IMPDH1 Antibody  
Catalog Number: 37655  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P20839
    NCBI Gene ID: 3614
    Gene Accssion: NP_001136045
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human IMP (inosine 5'-monophosphate) dehydrogenase 1
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:25-1:100
  • other_names：  
  • IMPD; RP10; IMPD1; LCA11; sWSS2608
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total IMPDH1 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.



 
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