Product Datasheet  
IL19 Antibody  
Catalog Number: 37650  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9UHD0
    NCBI Gene ID: 29949
    Gene Accssion: NP_037503
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human interleukin 19
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:50-1:200

  • other_names：  
  • MDA1; NG.1; ZMDA1; IL-10C
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total IL19 protein.
  • Applications：  
  • WB IHC
  • Background：  

  • The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.




 
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