Product Datasheet
IFNGR2 Antibody
Catalog Number: 37643
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P38484
NCBI Gene ID: 3460
Gene Accssion: NP_005525
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human interferon gamma receptor 2 (interferon gamma transducer 1)
- appl_detail:
- Western blotting: 1:2000-1:5000
- other_names:
- AF-1; IFGR2; IFNGT1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total IFNGR2 protein.
- Background:
- This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
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