Product Datasheet  
HNRNPL Antibody  
Catalog Number: 37624  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P14866
    NCBI Gene ID: 3191
    Gene Accssion: NP_001524
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to a region derived from internal residues of human heterogeneous nuclear ribonucleoprotein L
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:50-1:200
  • other_names:  
  • HNRPL; hnRNP-L; P/OKcl.14
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total HNRNPL protein.
  • Applications:  
  • WB IHC
  • Background:  
  • Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm.



 
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