Product Datasheet
R3HCC1L Antibody
Catalog Number: 37592
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q7Z5L2
NCBI Gene ID: 27291
Gene Accssion: NP_001243548
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human R3H domain and coiled-coil containing 1-like
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- PSORT; GIDRP86; GIDRP88; C10orf28
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total R3HCC1L protein.
- Background:
- C10orf28 (chromosome 10 open reading frame 28), also known as GIDRP88 (growth inhibition and differentiation-related protein 88) or putative mitochondrial space protein 32.1, is a 792 amino acid protein that exists as three alternatively spliced isoforms. The gene encoding C10orf28 maps to human chromosome 10, which spans nearly 135 million base pairs, makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman¡¯s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
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