Product Datasheet
GCSAM Antibody
Catalog Number: 37588
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8N6F7
NCBI Gene ID: 257144
Gene Accssion: NP_689998
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human germinal center-associated, signaling and motility
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- HGAL; GCAT2; GCET2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GCSAM protein.
- Background:
- This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms.?
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