Product Datasheet
GABRG2 Antibody
Catalog Number: 37584
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P18507
NCBI Gene ID: 2566
Gene Accssion: NP_000807
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human gamma-aminobutyric acid (GABA) A receptor, gamma 2
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
- other_names:
- CAE2; ECA2; GEFSP3
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GABRG2 protein.
- Background:
- This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
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