Product Datasheet
FBXO31 Antibody
Catalog Number: 37567
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q5XUX0
NCBI Gene ID: 79791
Gene Accssion: NP_079011
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human F-box protein 31
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- FBX14; Fbx31; FBXO14; pp2386
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total FBXO31 protein.
- Background:
- This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants.
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