Product Datasheet
TDGF1 Antibody
Catalog Number: 37506
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P13385
NCBI Gene ID: 6997
Gene Accssion: NP_003203
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human teratocarcinoma-derived growth factor 1
- appl_detail:
- Immunohistochemistry: 1:15-1:100
- other_names:
- CR; CRGF; CRIPTO
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TDGF1 protein.
- Background:
- This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.
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