Product Datasheet
CRLF2 Antibody
Catalog Number: 37496
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9HC73
NCBI Gene ID: 64109
Gene Accssion: NP_071431
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human cytokine receptor-like factor 2
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- CRL2; TSLPR; CRLF2Y
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CRLF2 protein.
- Background:
- The protein encoded by this gene is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene.
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