Product Datasheet
CLPTM1L Antibody
Catalog Number: 37492
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q96KA5
NCBI Gene ID: 81037
Gene Accssion: NP_110409
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human CLPTM1-like
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CLPTM1L protein.
- Background:
- Cleft lip and palate transmembrane protein 1-like protein?(CLPTM1-like protein), also known as?cisplatin resistance-related protein 9?(CRR9p), is a?protein?that in humans is encoded by the?CLPTM1L?gene.?CRR9p is associated with?cisplatin-induced?apoptosis.?CLPTM1L, which lies within a cancer susceptibility locus on chromosome 5 (5p15.33), has been found to be commonly over-expressed in lung tumors and to confer resistance to apoptosis caused by genotoxic agents in association with up-regulation of the anti-apoptotic protein, Bcl-xL.
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